St. Louis wears its pizza reputation like a badge. Locals debate sauce styles over coffee. Visitors hear rumors of cracker-thin squares and creative toppings, then line up to put those legends to the test. Pizza here isn’t just food; it’s a point of pride and a full-blown pastime. Whether you’re a die-hard fan of the classic St. Louis style or chasing a perfect Neapolitan crust, the hunt for the city’s best slice always sparks lively conversation.
After tasting my way through buzzing parlors, family-owned gems, and wood-fired marvels, I discovered there’s no single definition of “best.” Each spot is a chapter in the city’s pizza story, offering its brand of comfort, creativity, and flavor. If you’ve ever found yourself scrolling reviews while craving something cheesy, saucy, and perfect, you’re in the right place. Let’s dig into the most satisfying slices St. Louis has to offer.
Where to find the best pizza in St. Louis, MO
Here are some of the top spots to find the best pizza in St. Louis, MO:
- Anthonino’s Taverna
- Dewey’s Pizza – U-city
- Dewey’s Pizza – Kirkwood
- Pastaria
- Guido’s Pizzeria and Tapas
- Katie’s Pizza & Pasta Osteria
- Vito’s Sicilian Pizzeria & Ristorante
- Pizzeoli Wood Fired Pizza
- Katie’s Pizza & Pasta
- Farotto’s
1. Anthonino’s Taverna
Set on Macklind Avenue, Anthonino’s Taverna blends Greek and Italian comfort. The space feels old-school but buzzing, always filled with regulars and first-timers who know good pizza when they taste it. The crust lands just right—crisp, never too thin or doughy—and the sauce walks that tightrope between sweet and tangy.
My first visit, a server convinced me to try their signature St. Louis-style pizza with a cheese blend and hand-sliced pepperoni. It was easy to see why people rave. The flavors feel both bold and balanced, with toppings generous but never overwhelming.
Vegetarian or gluten-free? They’ve got real choices, not afterthought substitutions. If you’re stuck on what to order, the four-cheese pizza is a creamy, crowd-pleasing intro to their strengths—or explore their Mediterranean-inspired pies for a twist.
2. Dewey’s Pizza – U-city
Dewey’s Pizza – U-city is the kind of spot where you can catch up with friends over fresh, playful slices. Located on North and South Road, it’s modern but relaxed, with open kitchens that let you watch the dough spin—showmanship included.
I dropped by on a rainy evening and found the staff as warm as the crust. Try the “Green Lantern” pizza: bursts of garlic, mozzarella, artichokes, goat cheese, and spinach create a pie that feels fresh but indulgent. Their salads deserve a mention too, with inventive combinations that outshine typical sides.
Vegetarian and gluten-free options aren’t just an afterthought here. If you love variation, consider splitting two different specialty pies. That’s how you’ll get the true Dewey’s experience—curiosity rewarded by flavor.
3. Dewey’s Pizza – Kirkwood
Dewey’s Pizza – Kirkwood brings a friendly, upbeat vibe to North Kirkwood Road. The dining room buzzes with groups debating their favorite pizza, all while the staff work a polished open kitchen. Families and college friends alike fill the space, giving it the feel of a local hub.
I once stopped in for a late lunch and left with a new respect for their crust and toppings. The “Southwest BBQ Chicken” pizza is a favorite—smoky barbecue sauce, sharp cheddar, and roasted corn on a golden, chewy base.
This Dewey’s location plays the hits: inventive pies, crisp salads, gluten-free and veggie possibilities that don’t skimp on flavor. Build your own if you’re feeling creative, or just trust the seasonal specials for something new.
4. Pastaria
Pastaria in Clayton elevates pizza with a charm that feels modern and authentic at once. The open kitchen sends out an aroma of fresh dough and wood-fired smoke that hits you as soon as you walk in. Tiled walls and natural light set the stage for casual dinners and big celebrations alike.
During my visit, I tried the Margherita pizza. What sets it apart is the dough—it’s chewy and blistered from the oven, topped with San Marzano tomato, basil, and creamy mozzarella. Simple ingredients, but in balance, and each bite feels like a showcase in restraint.
Vegans and gluten-free folks find real choices here, not just substitutions. For a bit more adventure, the “Funghi” pizza brings roasted mushrooms and fontina that’s earthy and rich. Pastaria’s menu reflects an understanding of what makes pizza memorable: quality, simplicity, and just the right amount of flair.
5. Guido’s Pizzeria and Tapas
Guido’s Pizzeria and Tapas stands at the intersection of Italian comfort and Spanish flair, right on Shaw Avenue. The atmosphere strikes a balance between family-friendly and lively, making it easy to settle in whether you’re grabbing lunch or catching up late with friends.
The moment you’re seated, the aroma of bubbling cheese drifts from the kitchen. The St. Louis-style thin crust pizza here is what keeps regulars coming back—each slice offers crisp edges, a subtle herb kick, and just enough gooey mozzarella to keep things interesting.
I recommend the vegetable-loaded pizza or the classic Margherita, which highlights Guido’s focus on fresh, quality toppings and expert balance. Vegetarian, vegan, and gluten-free diners find solid choices, too. Guido’s blends tradition with a hint of the unexpected, making every pizza a discovery.
6. Katie’s Pizza & Pasta Osteria
Katie’s Pizza & Pasta Osteria fuses rustic Italian inspiration with local St. Louis creativity. The dining room fills with sunlight during the day and soft conversation at night, giving it a warm, easy-going atmosphere. Hand-tossed dough and inventive toppings set these pies ahead of the crowd.
My visit started with the roasted beet salad, but the star was the pizza. The “Fig & Squash” stood out for balance—sweet fig, roasted squash, creamy cheeses, and a crisp, chewy base. Each pizza links seasonal produce and invention, reflecting the kitchen’s playful approach.
Vegetarian diners find thoughtful options beyond just cheese. Gluten-free crust is available and doesn’t sacrifice on texture. If you want classic but crave a twist, the “Spring Vegetable” pizza is fresh, colorful, and satisfying. Katie’s proves that pizza can be traditional and bold all at once.
7. Vito’s Sicilian Pizzeria & Ristorante
Vito’s Sicilian Pizzeria & Ristorante brings a slice of Sicily to the middle of St. Louis. The lively restaurant sits near SLU, making it popular with both students and local families. The atmosphere leans cozy, with the smell of freshly baked dough wafting out to the sidewalk.
On my visit, it was impossible to resist their Sicilian-style square pizza. The crust is pillowy yet crisp at the edges, with toppings scattered generously but never overdone. The “Vegetali” pizza layers roasted vegetables and silky mozzarella, offering a medley of flavor in every bite.
This spot serves up satisfying gluten-free and vegan variations, so no one feels left out. Vito’s stands apart for authentic recipes, a welcoming staff, and pies that taste like they’re made with care.
8. Pizzeoli Wood Fired Pizza
Pizzeoli Wood Fired Pizza sits snug in Soulard, where exposed brick and candlelight set a relaxed, inviting scene. This isn’t your typical pizza spot—each pie is a tribute to artisan methods, using local farm ingredients and their signature wood-fired oven for rustic charm and a smoky edge.
The Margherita pizza sparkles here: the crust bubbles and blisters, while fresh basil and mozzarella melt into San Marzano tomato sweetness. Every ingredient feels intentional, from the dough’s texture to the scatter of herbs.
Those seeking plant-based or gluten-free options will find plenty of thoughtful, flavorful choices. For a flavor adventure, try the “Funghi e Cipolla,” where roasted mushrooms and caramelized onions shine. Pizzeoli offers pizza that feeds both nostalgia and curiosity—all with a distinct St. Louis twist.
9. Katie’s Pizza & Pasta
Katie’s Pizza & Pasta in Town and Country strikes a balance between cozy neighborhood favorite and buzzing hotspot for pizza lovers. This light-filled space feels stylish yet relaxed, perfect for lunch breaks or leisurely dinners. Hand-stretched dough and crunchy-chewy crust are what set their pizzas apart—it’s easy to notice even before the first bite.
I once ordered the “Eggplant Parm” pizza, and the combination of roasted eggplant, herby sugo, and creamy cheeses turned out to be one of those rare surprises that make you crave another visit. Every pizza bursts with seasonal produce and creative toppings, reflecting the kitchen’s happy mix of tradition and innovation.
Vegetarians and gluten-free guests have plenty of options, and the kitchen’s care shows in every detail. If you’re feeling adventurous, don’t skip the ever-changing specials or the “Spring Vegetable” pizza for a plateful of color and flavor.
10. Farotto’s
Farotto’s has been a Manchester Road mainstay for decades, where regulars chat with staff like it’s a family reunion. The atmosphere is easygoing yet welcoming, making it a trusted destination for those craving a classic St. Louis dining experience.
The pizza here stands out for its crackling-thin crust and generous sauce. Each pie is cut into squares, St. Louis style, so you can sample a mix of middle and edge bites. Their veggie pizza impressed me—a mountain of roasted vegetables layered so you get fresh flavor in every bite, not just cheese.
Those with dietary needs find gluten-free and vegan options that don’t feel like afterthoughts. Don’t be shy about trying any of the neighborhood’s favorite specialty pizzas—Farotto’s has a loyal following for a reason.
More Things to Try in St. Louis, MO
Frequently Asked Questions
What is St. Louis-style pizza?
St. Louis-style pizza is thin and crisp, often cut into squares. It uses a unique processed cheese blend and a slightly sweet tomato sauce, giving it a special character you won’t find elsewhere.
Where can I find the best St. Louis-style pizza?
Many local favorites compete for the title. Spots like Anthonino’s Taverna, Farotto’s, and Guido’s Pizzeria are top contenders, each serving their own spin on the classic thin crust and zesty sauce.
Are there vegetarian and gluten-free pizza options in St. Louis?
Absolutely. Most pizza places offer vegetarian and gluten-free choices, and some even have vegan options. Katie’s Pizza & Pasta and Dewey’s Pizza are especially known for their inclusive menus.
What other pizza styles are popular in St. Louis?
You’ll find everything from wood-fired Neapolitan pies at Pastaria and Pizzeoli to hearty Sicilian squares at Vito’s. The city’s pizza scene encourages variety, so you’re always a slice away from something new.
Can I get pizza delivered or for takeout?
Yes, nearly every pizzeria in St. Louis offers delivery, takeout, or both. Many also provide curbside pickup and online ordering for added convenience.