Finding that mythical slice of perfect pizza is an adventure anywhere, but Key West puts its own tropical spin on the quest. The island atmosphere wraps every bite in a whiff of ocean breeze, and the pizza joints here are anything but ordinary. I still think about wandering past glowing neon fronts with salt clinging to my flip-flops and the scent of crisped dough drawing me in. Whether you crave chewy Neapolitan pies, classic East Coast fare, or something wild topped with local produce, you’ll find a match.
Hungry travelers swear by the local charm and secrets baked into every pie. Some pizzerias are tucked behind historic homes, others spill onto the sidewalk with a casual vibe you won’t get anywhere else. Get ready for a shortlist of Key West’s finest pizza spots, each serving up a slice of local flavor that might just become your new favorite. If you’re looking to dodge the tourist traps and sink your teeth into something unforgettable, keep reading—your perfect slice could be closer than you think.
1. Clemente’s Trolley Pizzeria
Clemente’s Trolley Pizzeria brings a bit of New York attitude and Italian tradition to the heart of Key West. The brick oven sits inside a retro trolley car, so watching your pizza hit the flames is part of the show. There’s always a lively buzz here, especially when the handmade dough meets the wood fire and that unique smoky aroma drifts through the air.
The Margherita pizza is a crowd favorite—the crust blisters just right, and the tomatoes burst with flavor. If you like a twist, order the White Pizza, loaded with creamy ricotta and a good hit of garlic. Clemente’s also does gluten-free pies without skipping on taste, so everyone feels included. Quick service, generous toppings, and a slice of local flair are guaranteed.
2. Seaside Cafe at the Mansion
Seaside Cafe at the Mansion makes pizza an event, not just a meal. The café is perched right by the water, with breezes and ocean views that take any slice to a new level. Sitting at a shaded table, I remember how the salt air worked some kind of magic with the flavors coming from the wood-fired oven.
Their signature Island Pie is a stand-out. It balances tangy pineapple, zesty sauce, and bubbling cheese in a way that’s bright and fresh, never cloying. For a simple classic, the Margherita bursts with ripe tomatoes and peppery basil. The menu even has vegan and gluten-free options, so everyone can join in. Every pizza here tells a seaside story—fresh, light, and full of character.
3. Duetto Pizza and Gelato
Duetto Pizza and Gelato is the kind of spot where both locals and visitors strike up conversations at the counter. The pizza here is classic Italian, with thin, crisp slices you can actually fold—a rare find in Key West. The casual atmosphere made me feel right at home, and I ended up staying for “just one more slice.”
The Veggie Slice is a favorite, loaded with fresh seasonal toppings and gooey cheese. If you want something with depth, the White Pizza—oozing with creamy mozzarella—is a solid bet. And don’t skip their signature gelato as a cool finish. At Duetto, every bite feels like you’ve discovered a neighborhood secret that locals are happy to share.
4. Mr Z’s
There’s something about Mr Z’s that draws in the late-night crowd like moths to a neon sign. The counter always has a steady stream of folks after midnight, all craving that classic New York-style slice. After a long stroll down Duval, I grabbed a slice topped with garden-fresh veggies, and it hit every spot—crispy crust, stretchy cheese, and a sauce with the right punch.
Their veggie pizza is loaded and never skimps on the toppings. If you’re feeling adventurous, the stromboli is a hot contender—perfectly baked and packed with flavor. Mr Z’s proves that sometimes the best slice is the one you eat when the world is quiet and the hunger is loud.
5. Onlywood Pizzeria Trattoria
Onlywood Pizzeria Trattoria takes Neapolitan pizza seriously, with certification straight from the Associazione Pizzaioli Napoletani America. Stepping inside, you’ll hear Italian spoken in the kitchen and see fresh dough tossed with flair. The wood-fired oven sets the scene, filling the air with the unmistakable aroma of charred crust.
Their Margherita pizza is pure simplicity done right—pillowy soft in the center, crackling at the edges, and layered with bright tomatoes and creamy mozzarella. For something heartier, try the Ortolana piled high with roasted vegetables. Onlywood proves that even in Key West, you can savor true Italian craftsmanship, one chewy bite at a time.
6. Roostica Wood-Fire Pizzeria
Roostica Wood-Fire Pizzeria offers a cozy retreat away from the bustle of Old Town. The wood-fired oven takes center stage here, with flames licking the dough to a perfect golden char. The setting feels casual but special, where locals gather for an evening of hearty pies and conversation.
Their Verdura pizza stands out—generous with roasted veggies and bubbling mozzarella, it brings plenty of color and freshness to the table. The classic Margherita is always a winner, with an airy crust and that touch of smoke you only get from real wood fire. Vegan and gluten-free options mean no one misses out. At Roostica, every pizza looks and tastes like it was made just for you.
7. White Street Pizza And More!
White Street Pizza And More! is the kind of neighborhood spot where regulars and newcomers both feel right at home. The Italian brick oven turns out thin-crust pies with crispy edges and just the right touch of char. From the first bite, you can taste the craftsmanship in the dough, which always feels airy but still manages to hold up under layers of toppings.
The Veggie Lovers pizza is a bold choice here, loaded with seasonal vegetables that make each slice burst with flavor. Their Margherita is another must, with fresh basil and simple tomato sauce letting the crust shine. The cozy dining room and house-made desserts add to the inviting vibe—this is a place that makes you want to linger over every slice.
8. Onlywood Grill
Onlywood Grill brings Italian culinary flair to downtown Key West in a laid-back setting. The spectacular wood fire oven delivers not just pizzas but a sense of occasion every time the flames leap. Fresh ingredients and careful technique are the rule here, and you notice the difference in every bite.
Their Quattro Formaggi pizza is especially good, with a rich blend of cheeses that bubbles and browns until just right. For veggie fans, the Ortolana is loaded with roasted vegetables straight from the grill, offering smoky depth in every mouthful. Vegan and gluten-free pizzas make sure there’s something for everyone. It’s the sort of place where you’ll want to explore the menu past the first pie—and probably return for more.
9. Angelina’s Pizzeria
Angelina’s Pizzeria has been a go-to for fresh, satisfying pizza in Key West for more than thirty years. Walk up to the counter, and you’ll see the team stretching dough by hand and layering on crisp vegetables or gooey cheese. There’s a comforting, old-school vibe here—just good pizza, made without shortcuts.
Their Veggie pizza is a colorful standout, delivering a crunchy medley of peppers, onions, and mushrooms atop a perfectly chewy crust. The cheese pizza is another classic, and both vegetarian options shine thanks to the quality of fresh ingredients. Great for a casual bite after exploring Duval Street, Angelina’s is a must for anyone who loves a classic slice that never lets you down.
10. Pizza Joe’s
Pizza Joe’s serves up piping hot slices on Duval Street where the energy never dips. This is the spot you stumble into after sunset, drawn by the aroma of fresh-baked pizza wafting onto the sidewalk. The counter service is quick, and the team is always ready with a recommendation.
Their cheese pizza deserves special mention—stretchy, golden, and not overloaded. The veggie slice is another solid choice, with just enough crunch to feel satisfying without weighing you down. If you want classic, straightforward pizza in the heart of Key West, Pizza Joe’s delivers every time. It’s the perfect pit stop for a late-night craving or a quick lunch between adventures.
Frequently Asked Questions
What style of pizza is most common in Key West?
Most spots in Key West focus on New York–style thin crust or traditional Neapolitan, with a few wood-fired and artisan options thrown in for good measure.
Are there any vegan or gluten-free pizza options in Key West?
Absolutely. Many places, like Onlywood and Roostica, offer vegan-friendly and gluten-free pizzas, so everyone can enjoy a slice.
Which pizza places in Key West are open late?
Mr Z’s, Angelina’s, and Pizza Joe’s are known for serving pizza well into the early morning hours—great for night owls and late arrivals.
Can I get pizza delivered anywhere in Key West?
Delivery is common across the island. Most pizzerias and mainstream chains like Domino’s and Papa John’s deliver to hotels, rentals, and even marinas.
Is it easy to find vegetarian pizza in Key West?
Very easy. Most local pizza shops have at least one strong vegetarian option, often using plenty of fresh, local produce.
Are reservations needed for pizza places in Key West?
Typically, walk-ins are welcome. However, popular sit-down spots like Onlywood or White Street Pizza And More! can get busy, so a reservation is smart if you’re planning dinner for a group.