Best Pizza in Isle of Palms, SC

Finding great pizza on Isle of Palms isn’t a wild goose chase—it’s more like an unexpected joyride. My first bite here was at a small beachside spot after a full day in the sun. Hot cheese, a perfect crust, and the mix of salty air made it feel like the slice itself was part of the scenery. Isle of Palms may look laid-back, but its pizza scene is anything but lazy.

The local favorites, peppered with a few national names, blend unique coastal charm with familiar comforts. You’ll find wood-fired pies, classic New York slices, and creative local twists. Each place has its own way of making pizza more than just a meal—it becomes an experience worth remembering. So, whether you want a quiet slice near the dunes or you’re on a quest for the crispiest crust, the following list will steer you right.

1. Coastal Crust Wild Dunes

Coastal Crust Wild Dunes
Image by: TripAdvisor
5802 Palmetto Dr, Isle of Palms, SC 29451-3813
+1 843-886-7300
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Coastal Crust Wild Dunes feels like the living room you wish you had—airy, rustic, and always buzzing. I remember sitting beneath twinkling string lights, catching a whiff of wood-fired dough as the sun slipped away. The pizzas here are charred just right, with a crust that blends crunch and chew in every bite.

This spot stands out because of its attention to detail. Fresh ingredients top every pie, from basil still fragrant to creamy mozzarella that stretches just so. The kitchen doesn’t cut corners, and you can taste it in their classic Margherita or their seasonal special, loaded with local veggies.

If you’re deciding what to order, try the Wild Dunes Pie—tender sausage, peppery arugula, and roasted red peppers bring the Lowcountry sunshine right to your table. It’s the kind of place where one slice leads to another.

2. Domino’s Pizza

1400 Palm Blvd. Ste B, Isle of Palms, SC 29451
+1 843-886-4242
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Domino’s Pizza on Isle of Palms is the spot where familiar comfort meets convenience. Late one evening, I watched the rain come down while enjoying a thin-crust pizza in my car—a surprisingly cozy escape. Consistent flavors and lightning-fast service make this Domino’s a go-to for families, beachgoers, and locals.

You get the classics here, but each pizza arrives hot, crisped just right, and topped to order. The selection stretches from the foldable New York Style to the robust Handmade Pan, so you can always match your mood.

If you’re stuck on what to try, the Pacific Veggie is a solid bet—brimming with fresh vegetables and melty cheese. For something heartier, the Pizza Cheesy Bread works as a side or a meal, delivering that classic Domino’s comfort bite after bite.

3. Pizza Hut

Pizza Hut
Image by: YellowPages
1515 Palm BlvdIsle Of Palms, SC 29451
(843) 886-5759Call
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Pizza Hut on Palm Blvd brings a comforting sense of nostalgia. I’ve grabbed takeout here after a late beach sunset, enjoying that familiar aroma as the box warmed my lap on the drive home. The Isle of Palms location stays true to Pizza Hut’s roots—reliable, consistent, and crowd-pleasing.

The highlight remains their Original Pan Pizza. The crust is thick, golden, and just the right kind of crispy on the edges. If you like to start (or end) your meal with something extra, the breadsticks here have that signature soft center and savory seasoning.

Don’t skip the Veggie Lover’s or Cheese Lover’s pizza; both deliver layers of flavor with each slice. Sometimes, all you want is a solid, classic pie—and Pizza Hut fits the bill.

4. Banana Cabana

Banana Cabana
Image by: YellowPages
1130 Ocean BlvdIsle Of Palms, SC 29451
(843) 886-4361Call
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Banana Cabana is that easygoing beachside retreat everyone wishes they’d stumbled across. I once ducked in after a swim, sand still on my feet, and felt instantly at home. This spot’s vibe is as sunny as its name, and their pizza surprises with flavor and freshness.

Unlike more formal places, you can show up here in your flip-flops and leave with a slice in hand. Their pizzas lean casual, with generous toppings and a soft, chewy crust that matches the relaxed atmosphere.

The Veggie Pizza here is a standout, loaded high with crisp peppers and mushrooms. If you’re pairing it with the sea breeze and a group of friends, there’s hardly a better choice. Banana Cabana keeps things simple, satisfying, and unpretentious.

5. Steel City Pizza Co.

1440 Ben Sawyer BlvdMount Pleasant, SC 29464
(843) 856-2525Call
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Steel City Pizza Co. brings a slice of Pittsburgh’s big-hearted food culture to the Lowcountry. On my last visit, a classic Steelers game played in the background while the aroma of bubbling cheese filled the space. This spot is about flavor, size, and a little bit of Northern charm in every bite.

The pies here are hearty, with a crust that lands in the ideal spot between chewy and crisp. Every pizza is handmade, topped to the edges, and loaded with fresh, quality ingredients.

Try the Pittsburgher Pizza—think roasted veggies, red onions, and a punchy sauce, all piled high. It’s the kind of pizza that brings people together, just as the best neighborhood joints do.

6. Deroma’s Pizzeria

1948 Long Grove DrMount Pleasant, SC 29464
(843) 972-1780Call
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Deroma’s Pizzeria feels like a little piece of Italy tucked into Mount Pleasant. I dropped by after hearing locals rave and wasn’t disappointed—the aroma of baked dough and herbs greets you at the door. There’s a genuine, homey atmosphere here that sets Deroma’s apart from chain shops.

The pizza is all about tradition, which means no shortcuts. Their dough is made from scratch and their sauce features a tang that comes only from slow-cooked tomatoes. Each pie boasts a golden, blistered crust, a nod to classic techniques.

The Margherita pizza shines; its balance of cheese and tomato highlights the pizzeria’s commitment to doing things right. If you crave something heartier, the Veggie Lovers pie is loaded without being heavy, making it a favorite for sharing.

7. Papa Johns Pizza

Papa Johns Pizza
Image by: YellowPages
1145 Johnnie Dodds BlvdMt Pleasant, SC 29464
(843) 884-6666Call
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Papa Johns Pizza in Mount Pleasant is my tried-and-true stop for reliable takeout after a long day. I’ve lost count of the times their fast service has saved my evening plans. The draw here is the consistently fresh dough and their signature, tangy tomato sauce.

This shop builds on simplicity—classic recipes, fresh ingredients, and a crust that manages to please both deep-dish and thin-crust fans. Every pizza arrives piping hot and exactly as ordered.

The Garden Fresh Pizza is a highlight, loaded with crisp veggies that keep their texture, while the cheese achieves perfect stretch. If you prefer a little bite, the thin-crust options are golden and satisfying. Papa Johns makes convenience feel just a little bit special.

8. Grimaldi’s Pizza

Grimaldi's Pizza
Image by: YellowPages
1244 Belk DrMt Pleasant, SC 29464
(843) 971-9368Call
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Grimaldi’s Pizza in Mount Pleasant captures the spirit of Brooklyn classic style, but in a sunny South Carolina setting. My first visit was a revelation: the scent of coal-fired dough hit me before I even sat down. This spot stands out for its use of a traditional brick oven and a dough recipe passed down for generations.

The crust here tells the story—thin, crispy at the edge, with just the right char underneath. Each pie is built with house-made mozzarella and a vibrant sauce, resulting in slices that have a true Italian bite.

The Margherita is the signature order, but the White Pizza with fresh garlic and ricotta is equally tempting. If you value authenticity and a perfect blistered crust, Grimaldi’s is a top choice near Isle of Palms.

9. Slice

1150 Hungryneck BlvdMount Pleasant, SC 29464
(843) 388-4071Call

Slice is that neighborhood pizza place where time seems to slow down in the best way. I once ducked in after a drizzle, finding a warm spot by the window with a view of the rain. The atmosphere is friendly and unfussy, and the pies have a homemade feel that keeps locals coming back.

This spot gets the basics right—hand-tossed dough, sauces made in-house, and cheese that melts just so. Pizzas come out with golden crusts and generous toppings, leaning into classic combos and creative specials.

The Veggie Pie is worth a try; each bite is stacked with fresh peppers, onions, and mushrooms. If you’re after something with a bit of zing, their white pizza with ricotta and spinach has a devoted following.

Frequently Asked Questions

What’s the best pizza place on Isle of Palms for dine-in?
Coastal Crust Wild Dunes is a standout for dine-in. The setting is relaxed and the pizzas are made with care, offering both comfort and quality.

Do pizza places on Isle of Palms offer delivery?
Yes, most spots like Domino’s, Pizza Hut, and Papa Johns provide delivery. Some local pizzerias offer their own delivery or work with apps for convenience.

Are there any vegetarian pizza options available?
Plenty. Most menus include classic veggie pies, and local favorites like Grimaldi’s and Banana Cabana feature fresh, vegetarian-friendly toppings.

Which pizza spots are open late on Isle of Palms?
Domino’s and Pizza Hut typically have the latest hours, so they’re a good choice for late-night cravings.

Can I find gluten-free pizza near Isle of Palms?
Many chains such as Domino’s and Pizza Hut now offer gluten-free crust. It’s always smart to double-check with the shop before ordering.

Where can I get pizza by the slice?
Slice and some casual beachside pizzerias often sell pizza by the slice—perfect for a quick bite during a beach day.

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