Some towns think they know pizza. Greenville lives it. This slice-loving city rolls out the dough for every taste, from bubbling brick-oven classics to new-wave wood-fired wonder, each spot with its own story and style. You might have walked down Main Street on a Saturday, catching that whiff of freshly baked crust blending into the sound of live music—the type of moment when choosing where to eat feels like a sacred duty.
It’s a decision I’ve never taken lightly. My search for the best pizza in Greenville has meant crispy corners, late-night detours, and the joy of discovering local legends hidden between barbershops and galleries. Here’s the inside track: I’ve forked through menus, quizzed chefs, and argued over toppings with friends who act like pineapple is a political stance, all to find the pizzerias you’ll want to visit again and again. If you’re ready for slices worthy of obsession, you’re in the right place.
Where to find the best pizza in Greenville, SC
Here are some of the top spots to find the best pizza in Greenville, SC:
- Trio – A Brick Oven Cafe
- Antonino Bertolo’s Pizza and Wine Bar
- Brixx Wood Fired Pizza + Craft Bar
- Myles Pizza Pub
- Belladina’s Pizzeria
- Sidewall Pizza Company – Downtown Greenville
- Mellow Mushroom Greenville
- Tito’s Restaurant Pizzeria
- Coastal Crust
- World Piece
1. Trio – A Brick Oven Cafe
Step inside Trio and you’ll feel like you’ve found a pizza hideaway locals want to keep secret. The glow from the gas lanterns and the energy of downtown swirl together, setting the scene for some of the best wood-fired slices in Greenville. Their dough is crackly, never chewy, and the sauces have a garden-fresh punch you can taste in every bite.
If you’re unsure what to order, start with the Roast Chicken & Basil Pesto pizza—it’s creamy, herby, and somehow decadent but light. The Roma & Sun-Dried Tomato option also bursts with flavor, showing off the kitchen’s attention to the details. Can’t eat gluten or dairy? Trio caters to just about everyone, so nobody feels left out.
2. Antonino Bertolo’s Pizza and Wine Bar
There’s history in every slice at Antonino Bertolo’s Pizza and Wine Bar. Family recipes straight from Sicily meet classic New York style, right on Main Street—if ever there was a spot to order “the usual,” this is it. The crust is thin but has character, and every bite gives you that perfect balance of crisp and chew.
My go-to is the Classic Cheese or Margherita; the cheese bubbles just right, and the sauce pops with Sicilian spices. Their signature dough uses pure olive oil with a kiss of honey—you can actually taste the subtle sweetness. If you’re feeling adventurous, try a white pizza or a veggie pie. This pizza proves that tradition can be deliciously simple.
3. Brixx Wood Fired Pizza + Craft Bar
+1 864-286-1070
Brixx Wood Fired Pizza + Craft Bar feels like a party, whether you’re celebrating or just catching up. The aroma of their crackling wood-fired oven is irresistible, and the menu has a clever way of welcoming every kind of eater—from gluten-free fans to plant-based diners.
One bite of the Florentine pizza and you’ll see why Brixx is a favorite. Wilted spinach, fresh tomatoes, and creamy mozzarella melt together on a thin, smoky crust. If you’re in the mood for a twist, try their seasonal veggie pies or build your own for a personalized spin. Brixx makes pizza an experience, not just a meal.
4. Myles Pizza Pub
Walking into Myles Pizza Pub, you’ll lose count of how many pizza boxes line the walls—each a nod to their loyal following. The atmosphere is unpretentious, but the pizzas are anything but ordinary; piled high, with toppings that hit every corner, these pies practically dare you to finish a slice.
The signature here is the Loaded Deluxe. There’s a mountain of fresh veggies and gooey cheese on a thick, chewy crust. For something classic, the Veggie works wonders, delivering that oven-roasted flavor with a satisfying crunch. Myles has a knack for generous portions without cutting corners on quality, and that’s why regulars return week after week.
5. Belladina’s Pizzeria
If you’re craving a true taste of Italy in Greenville, Belladina’s Pizzeria makes good on every promise. This family-owned spot pours heart into its craft, using ingredients straight from Italy and recipes handed down through generations. You can taste the difference in every bite; the crust alone is a masterclass in texture—thin, crisp, and just the right amount of char.
Their Margherita Pizza is a standout, layered with silky mozzarella and vibrant tomato sauce, finished off with aromatic basil. For a punch of flavor, the Quattro Formaggi offers a creamy, savory blend of cheeses. Belladina’s captures the warmth of an Italian kitchen, making you want to linger a little longer at your table.
6. Sidewall Pizza Company – Downtown Greenville
Sidewall Pizza Company in downtown Greenville feels less like a restaurant and more like an extension of your own kitchen if your kitchen was run by pizza fanatics. The toppings here are as fresh as the vibe, with a playful, modern menu that invites repeat visits. The patio is a genuine treat on sunny evenings, making it a go-to for casual gatherings or cravings that won’t quit.
If you’re unsure where to start, the Hawaiian or the Margherita Pie stand out, each offering a unique twist. The crust is crisp yet floppy in all the right places. Try a gluten-free base or vegan cheese without missing a beat. Sidewall delivers pizza that feels good—both in flavor and experience.
7. Mellow Mushroom Greenville
Mellow Mushroom Greenville is where imagination and pizza live side by side. The funky, art-filled interior and lively music set the tone for pizza that’s anything but basic. Every pie starts with a distinctive spring water crust, baked to a perfect golden edge with just the faintest crunch.
The Kosmic Karma Pizza is a local legend, piled with tangy sun-dried tomatoes, fresh spinach, and a swirl of pesto that makes for an unforgettable mouthful. For purists, their classic Veg Out piles on colorful veggies with finesse. Mellow Mushroom doesn’t just serve pizza—it serves creative, crave-worthy comfort that keeps you coming back, no matter your pizza preferences.
8. Tito’s Restaurant Pizzeria
Tito’s Restaurant Pizzeria is the kind of place where familiar faces and big slices go hand in hand. This local favorite wins hearts with a simple combination: friendly service and pizza that brims with homemade flavor. The space feels cozy, perfect for family dinners or casual meetups after work.
The Veggie Pizza is the real winner here, stacked with crisp peppers, onions, and ripe tomatoes, all layered over a chewy, golden crust. Their sauce has a subtle sweetness that sets every pie apart. If you want something that tastes just like a classic neighborhood pizzeria should, Tito’s delivers—both literally and figuratively.
9. Coastal Crust
Coastal Crust combines neighborhood charm with the romance of wood-fired pizza. The renovated garage setting buzzes with character and the scent of singed dough drifting through the air. On weekends, nothing beats sitting under string lights, watching pies slide in and out of the fiery oven.
The Margherita is a standout—fresh basil, milky mozzarella, and tangy tomato sauce sing on a blistered, airy crust. Feeling bold? Try their seasonal veggie pie for a creative twist you won’t find anywhere else. Coastal Crust captures the unfussy essence of a perfect pizza night, marrying great atmosphere with artisan technique in every slice.
10. World Piece
+1 864-568-5221
World Piece feels like a hidden hero on Greenville’s pizza scene. The menu manages to span both classic comfort and inventive new flavors, giving each pie a personality of its own. The setting is unfussy, making it an easy choice for laid-back nights or a quick lunch with friends.
The New York-style Cheese Pizza serves as proof that simple can be spectacular—crispy bottom, stretchy cheese, and a tangy tomato sauce. If you want to branch out, try one of their veggie-loaded specialties. World Piece stands apart for its consistency and the passion you can taste in every slice. You walk away full, and somehow, always a little happier.
More Things to Try in Greenville, SC
Frequently Asked Questions
What pizza places in Greenville offer vegan or gluten-free options?
Many top spots, like Sidewall Pizza Company, Mellow Mushroom, and Brixx Wood Fired Pizza, offer both vegan cheese and gluten-free crusts. Each location is great for those with dietary preferences or restrictions.
Where can I find authentic Italian-style pizza in Greenville?
Head to Belladina’s Pizzeria or Antonino Bertolo’s Pizza and Wine Bar for pies that showcase true Italian flavors and ingredients. Their dough, sauces, and cheese reflect family recipes and traditional techniques.
Is there anywhere to get New York-style pizza in Greenville?
World Piece and Antonino Bertolo’s are well-known for their New York-style slices. Expect thin, foldable crusts and a classic tomato-to-cheese ratio that’s on point.
Do any local pizza places in Greenville have outdoor seating?
Absolutely. Trio, Coastal Crust, and Sidewall Pizza Company all offer outdoor seating. Their patios create the perfect setting for enjoying fresh slices under the Carolina sky.
Which pizza restaurants are good for families or large groups?
Mellow Mushroom Greenville, Myles Pizza Pub, and Tito’s Restaurant Pizzeria are family favorites, ideal for groups looking for casual, spacious dining and plenty of kid-friendly options.
Are there options for late-night pizza in Greenville?
Yes, Antonino Bertolo’s and Brixx Wood Fired Pizza both offer late-night hours, so you never have to go without a slice when a craving hits after dark.