The scent of baking crust drifts down the coastline, and you follow it past neon signs and oak trees heavy with humidity. Biloxi, a city where blues riffs meet salty breeze, also happens to harbor a surprising amount of good pizza—if you know where to look. It’s not just about cheese and sauce here; it’s an ongoing search for bites that actually matter after a long day on the Gulf.
I’ve spent evenings sampling slices in local dives where regulars rattle off orders before the server gets to the table. From airy New York styles to crisp-edged Sicilian squares, I’ve tasted notes of real craft and fresh obsession. If you’re after the truth behind Biloxi’s best pizza—honest reviews, no sugarcoating—you’re in the right spot. Keep reading, and you just might end up planning your dinner before you finish this list.
Where to find the best pizza in Biloxi, MS
Here are some of the top spots to find the best pizza in Biloxi, MS:
- Big Play Entertainment Center
- Pop’s Pizzeria
- Pie Five Pizza Co.
- The Sicilian II
- Sicily’s Pizza
- Farruggio’s Pizzeria
- C. A. Sarducci’s Pizzeria
- Pisanos Pizzeria
- New York Pizza
- Domino’s Pizza
1. Big Play Entertainment Center
Big Play Entertainment Center isn’t your run-of-the-mill pizza stop. Here, pizza comes with a side of glowing arcade lights, lively families, and a menu full of variety. It’s a place where you can split a hot pie while your friends go head-to-head at air hockey.
I remember biting into their margherita pizza—crisp crust, fresh basil, just the right amount of sauce. Their classic cheese pizza also hits the right combination of gooey, golden, and flavorful. Even if you bring a crew, the kitchen turns out pies fast, perfect for sharing.
If you’re looking for gluten-free options, Big Play has you covered. Looking for more than pepperoni? Try their veggie pizza, which actually packs flavor, not just filler. After the games, it’s the perfect wind-down bite.
2. Pop’s Pizzeria
Pop’s Pizzeria draws you in with its laid-back vibe and friendly service. It’s the kind of spot where locals actually know your name. The dough is made in-house and you can taste the difference with every slice—chewy, golden and never bland.
On my last visit, the veggie pizza was a standout. Big slices, loaded with fresh toppings and real mozzarella set the standard for what a Biloxi pie should be. There’s a clear sense of pride here, both in the kitchen and at the tables.
If you’re in the mood for a classic, the margherita pizza is a safe bet. Full of bright tomato flavor and balanced herbs, it’s a slice that showcases Pop’s commitment to simple, satisfying food.
3. Pie Five Pizza Co.
Pie Five Pizza Co. pulls you in with a modern, build-your-own setup that moves fast but never feels rushed. Here, you watch your pizza stack up ingredient by ingredient—crust, sauce, toppings, cheese—right in front of you.
On my visits, the classic Tuscan Marinara always stands out. It’s tangy, all-natural, and ties everything together without that artificial aftertaste. The hand-cut veggie options taste garden fresh, and if you prefer gluten-free, their crust is crisp and surprisingly flavorful.
I’m partial to the Farmer’s Market pizza: roasted veggies laid out on that addictive crust. For those who like to experiment, you can mix and match until you hit your perfect bite. Pie Five lets you take charge, but still keeps the quality high.
4. The Sicilian II
The Sicilian II feels like you’ve walked into someone’s well-loved kitchen, not just a restaurant. Family recipes passed down for generations give real character to every pizza, and you can taste that extra bit of care in each bite.
The crust stands out—pressed just the right thickness, golden at the edges, and tender inside. The cheese pizza here is anything but ordinary, bubbling with rich mozzarella and their signature sauce that’s both tangy and sweet.
If you’re craving something classic, the margherita pizza is a winner. The basil is fresh, tomatoes bright, and the olive oil drizzle ties it all together. The Sicilian II isn’t just about filling you up; it’s about feeding you like you’re part of the family.
5. Sicily’s Pizza
Sicily’s Pizza surprises you with how much flavor can come out of a small, unpretentious spot. It’s the kind of place where locals drop in for a quick pie after work but end up chatting with staff about last night’s game.
I’ve sat down for lunch and watched pans come out of the oven with crusts golden and bubbly. The veggie pizza here manages to be hearty, loaded with ripe tomatoes, crisp peppers, and plenty of cheese.
If you want to taste their specialty, go with the classic cheese or margherita. The sauce stands out—zesty, never overpowering, it brings the whole slice together. Sicily’s Pizza knows how to balance comfort with quality.
6. Farruggio’s Pizzeria
Farruggio’s Pizzeria delivers more than just pizza—it offers an energetic setting where you can catch a game or enjoy the breeze from the deck. This spot feels like a cross between a classic pizzeria and a coastal hangout, making it great for groups.
On my visit, the thin-crust cheese pizza was a standout—perfectly charred at the edges, with a nice, stretchy cheese pull. The dough had just a touch of chew, which kept every bite satisfying.
If you’re in the mood for something more loaded, try their veggie pizza. Fresh toppings and a tangy sauce give each slice a balanced kick. Farruggio’s nails that just-right mix of flavor and fun.
7. C. A. Sarducci’s Pizzeria
C. A. Sarducci’s Pizzeria feels old-school, in the best way. The space is no-frills, but the focus is squarely on turning out solid pies and keeping regulars happy. That’s the charm—you know what you’re getting every time you walk in, and it rarely disappoints.
My favorite order is the simple cheese pizza. The crust strikes a sweet spot, landing between crisp and chewy, and the sauce is tangy but never sharp. Not too much cheese, but just enough for a balanced melt that keeps you coming back for another slice.
For a heartier option, try their veggie pizza. It’s loaded with fresh, colorful toppings, each adding texture and flavor. Sarducci’s shows that good pizza doesn’t need a gimmick—just fresh ingredients and know-how.
8. Pisanos Pizzeria
Pisanos Pizzeria brings a bit of big city flavor to the heart of Biloxi’s historic Howard Avenue. The interior buzzes with energy, and slices arrive hot from the oven without much of a wait. There’s a neighborhood feel here—not intimidating, just genuinely friendly.
On my last trip, I dove into their cheese pizza. The crust delivered that wood-fired crunch, while the mozzarella stretched with every bite. It’s the kind of pizza that pairs perfectly with good company or an afternoon stroll in the arts district.
For adventurous eaters, the veggie pizza is a must. Each topping tastes fresh, with nothing thrown on just for show. Pisanos nails the essentials and adds a dash of personality to every slice.
9. New York Pizza
New York Pizza at Edgewater Mall manages to channel that classic East Coast vibe right on the Mississippi Gulf. The big, foldable slices come out hot, with just enough cheese to create that signature stretch as you bite in.
There’s no fuss here—just quick service and a steady stream of mall shoppers grabbing lunch or dinner. The cheese pizza brings familiar comfort, with a thin crust that’s crispy on the bottom and soft in the middle.
If you want to taste what they do best, try the margherita or veggie option. Both show off fresh toppings and plenty of flavor, making New York Pizza an easy stop when you need quality in a hurry.
10. Domino’s Pizza
Domino’s Pizza on Pass Road is the definition of reliable. Late-night cravings or lunchtime rush—this spot turns out hot, consistent pies every time. It’s easy to pick up on the way home or get delivered if you’ve had a long day and want to skip the kitchen.
I’ve tried their thin crust and handmade pan pizzas here, and both come out with a satisfying crunch and gooey cheese. The Veggie pizza loads up on peppers, olives, and mushrooms, keeping things light but not bland. Quick service means your order won’t sit around getting cold while you wait.
If you’re indecisive, the classic cheese pizza is always spot on—simple, cheesy, and comforting. Domino’s makes getting pizza easy, whether you want a basic pie or to go all out on toppings.
More Things to Try in Biloxi, MS
Frequently Asked Questions
What pizza places in Biloxi offer vegetarian or vegan options?
Many pizzerias in Biloxi, like Pie Five Pizza Co., The Sicilian II, Pop’s Pizzeria, and Domino’s, have vegetarian pizzas and some vegan-friendly ingredients. Customized veggie pies are widely available.
Are there gluten-free pizza options in Biloxi?
Yes, a few spots—such as Big Play Entertainment Center and Pie Five Pizza Co.—offer gluten-free crusts. It’s best to call ahead since options and availability can vary by day.
Which pizza place delivers late in Biloxi?
Domino’s, Pizza Hut, and Little Caesars offer late-night delivery. Local pizzerias like Pop’s or The Sicilian II generally close earlier, so check ahead for hours.
Where can I find authentic New York-style pizza in Biloxi?
New York Pizza at Edgewater Mall specializes in classic, foldable New York slices. Domino’s and Pop’s also have options inspired by the city that never sleeps.
Is it easy to find a family-friendly pizza spot in Biloxi?
Many places are great for groups and families. Big Play Entertainment Center, Farruggio’s Pizzeria, and Sicily’s Pizza all cater to kids and relaxed gatherings with plenty of seating and laid-back vibes.