Best Pizza in Cape Girardeau, MO

I love pizza, and Cape Girardeau, MO, has some of the best. This town is packed with amazing pizza places. Each spot has its own unique vibe and delicious pies. Trust me, you’re in for a treat!

So, what’s the best pizza in Cape Girardeau? You’ll find excellent choices like Pagliai’s Pizza & Pasta and Rosati’s Pizza. Each one serves tasty pizza with fresh toppings. They have something for everyone, whether you love classic pepperoni or unique creations.

I can’t wait to share my favorites with you. You’ll find out what makes each pizzeria special. Get ready to explore the tasty pizza scene in Cape Girardeau!

Top 10 Pizza in Cape Girardeau, MO

1. Pagliai’s Pizza & Pasta(Cape Girardeau)
2. Rosati’s Pizza
3. Speck Pizza
4. Encore pizzeria + Kitchen
5. Papa Johns Pizza
6. Papa Murphy’s | Take ‘N’ Bake Pizza
7. Domino’s Pizza
8. Imo’s Pizza
9. Minglewood Brewery
10. Little Caesars Pizza

1. Pagliai’s Pizza & Pasta(Cape Girardeau)

Pagliai’s Pizza & Pasta is a favorite of mine. It’s located at 1129 Broadway St. This place feels cozy and welcoming. It’s the perfect spot for pizza lovers!

I had their Margherita pizza once, and wow! The crust was so crisp. The fresh basil and gooey mozzarella were a dream. I can still taste it! Their spaghetti and meatballs are also amazing. The flavors are just like in Italy.

What makes Pagliai’s special? It’s the friendly vibe and delicious food. You get this homey feeling when you walk in. I suggest you try the Margherita pizza and spaghetti. You won’t be disappointed! Enjoy every bite!

2. Rosati’s Pizza

Rosati’s Pizza is a must-try place in Cape Girardeau. It’s located at 2136 William St. The vibe is lively, and the space is cozy. They serve amazing Chicago-style deep-dish pizza!

My first visit was unforgettable. I ordered the deep-dish pizza, and it was huge! The cheese was so melty, and the crust was perfectly crispy. I remember loving every single bite. Their garlic bread is a tasty addition, too. You have to try it!

What really sets Rosati’s apart is their rich flavors. Their pizzas are always fresh and filling. I highly suggest the Chicago deep-dish pizza. It shows off their great style and quality. It’s a delicious slice of Chicago right here! Enjoy every moment!

3. Speck Pizza

Speck Pizza is one of my favorite spots in Cape Girardeau. It’s located at 430 Broadway Street. The atmosphere is super chill and inviting. You can enjoy your meal inside or outside, which is nice!

My first time there was great. I ordered a wood-fired pizza and was blown away. The crust was so crispy and had a lovely smoky flavor. I remember loving the fresh toppings, too. It felt really special!

What really makes Speck Pizza stand out? It’s all about quality. They use fresh ingredients and put a lot of care into each pizza. I highly recommend trying the Margherita pizza. It’s simple yet so delicious. You’ll taste the difference! Enjoy every slice!

4. Encore pizzeria + Kitchen

Encore Pizzeria + Kitchen is such a cool spot in Cape Girardeau. It’s right at 46 Main Street. The atmosphere is casual and welcoming. You can sit inside or out, which is nice on a sunny day!

I remember my first visit so well. I decided to try their special pizza. Wow, it was delicious! The crust had this perfect crunch, and the toppings were super fresh. Each bite was full of flavor!

What really makes Encore shine is their fun menu. They have some really creative pizza options. I highly recommend the BBQ Chicken pizza. It’s sweet, smoky, and so tasty. You’ll want to eat every last slice! Enjoy your time there; it’s a real treat!

5. Papa Johns Pizza

Papa John’s Pizza on N Sprigg Street is my go-to for a quick, tasty bite. It’s super casual and laid-back. They’ve got a great selection of pizzas, wings, and sides.

So, one time, I grabbed a Works pizza for a movie night. The crust was soft, and the toppings were so fresh. Everyone at the party loved it!

What’s cool about Papa John’s is their quality. You always know you’re getting good stuff. I really like their BBQ Chicken pizza. It’s tangy and delicious. And those garlic knots? Definitely worth it. Enjoy your pizza night!

6. Papa Murphy’s | Take ‘N’ Bake Pizza

Papa Murphy’s | Take ‘N’ Bake Pizza at 2510 William St, Cape Girardeau is a pizza lover’s dream. You choose your toppings, then bake it at home. It’s super fun, especially for families.

One night, I grabbed a Chicken Garlic pizza. As it baked, my kitchen smelled heavenly. And the taste? Pure deliciousness—fresh, garlicky, perfect.

What’s cool about Papa Murphy’s? You control the ingredients. Everything is super fresh. Plus, it’s budget-friendly. Next time, try the Cowboy pizza. It’s full of savory goodness: sausage, pepperoni, mushrooms. Trust me, it’s a winner!

7. Domino’s Pizza

Domino’s Pizza on Sprigg Street is always my go-to. It’s easy to spot, super convenient, and affordable. They offer curbside pickup, delivery, and takeout. Plus, it’s wheelchair-accessible, which I think is great.

One time, I ordered their ExtravaganZZa pizza. It came quick, even though it was raining. The crust was crunchy, and the toppings were fresh. It was so good I almost didn’t share.

What really sets Domino’s apart is the variety. There’s something for everyone. Their Chicken Bacon Ranch pizza? Oh wow, it’s creamy, smoky, and unforgettable. Definitely worth trying.

So, if you’re hungry, give them a shot. You won’t regret it. Seriously, just order.

8. Imo’s Pizza

Imo’s Pizza is a favorite spot of mine. It’s located at 1008 N Kingshighway St in Cape Girardeau. I love their curbside pickup and delivery options. You can also sit outside or inside. The vibe is casual, and it feels welcoming.

Last time I visited, I got the Deluxe Pizza. Wow! The thin crust was super crispy, and the Provel cheese? So creamy and delicious! I couldn’t help but savor every bite.

What makes Imo’s stand out is that unique Provel cheese. It really makes their pizzas special. If you’re looking for something tasty, definitely try the Deluxe Pizza. It has all the best toppings and shows why Imo’s is so popular. You won’t be disappointed!

9. Minglewood Brewery

Minglewood Brewery is such a fun place. It’s on Broadway Street, right in Cape Girardeau. The vibe there? Super chill. Perfect for relaxing. They do takeout, delivery, and even outdoor seating. So, no worries about how to enjoy your food.

I remember trying their pizza one night. Oh, the crust! It was crispy and so good. The toppings were fresh and full of flavor. Honestly, it was just perfect. It made my whole day better.

Their craft beer is awesome too. They know how to pair it with their food. The BBQ Chicken pizza? Wow. It’s smoky, tangy, and downright tasty. Add a cold beer, and you’re set. It’s pure happiness on a plate.

10. Little Caesars Pizza

Little Caesars Pizza is one of my favorite spots. It’s located at 310 N Kingshighway St in Cape Girardeau. I love how quick and easy it is. You can get pizza, wings, and those yummy breadsticks for a great price!

When I went there last time, I was in and out in no time. I went for their Hot-N-Ready pizza. It was fresh and ready right away. The crust was nice and crunchy. Every bite was so satisfying!

What stands out about Little Caesars? It’s fast and super affordable. You really get a lot for what you pay. You’ve got to try the Crazy Bread. It’s buttery and delicious—definitely a must-have!

Map of Pizza in Cape Girardeau, MO

Choosing the Right Restaurant for You

With 10 excellent places, here’s a quick comparison to help you decide:

Restaurant	Price	Seating	Takeout	Delivery	Wheelchair	Reservation
Pagliai’s Pizza & Pasta(Cape Girardeau)	Moderate	Yes	Yes	Yes	Accessible	No
Rosati’s Pizza	Moderate	Yes	Yes	Yes	Accessible	–
Speck Pizza	Moderate	Yes	Yes	Yes	Accessible	–
Encore pizzeria + Kitchen	Moderate	Yes	Yes	Yes	Accessible	–
Papa Johns Pizza	Inexpensive	Yes	Yes	Yes	Accessible	No
Papa Murphy’s | Take ‘N’ Bake Pizza	Inexpensive	No	Yes	Yes	Inaccessible	No
Domino’s Pizza	Inexpensive	–	Yes	Yes	Accessible	–
Imo’s Pizza	Moderate	Yes	Yes	Yes	Accessible	No
Minglewood Brewery	–	Yes	Yes	Yes	–	No
Little Caesars Pizza	Inexpensive	No	Yes	Yes	Accessible	No

Frequently Asked Questions

1. What are the best pizza places in Cape Girardeau?
Oh, I love Pagliai’s Pizza & Pasta and Rosati’s Pizza! Speck Pizza is also a favorite. Each place has its own unique taste.

2. Does Cape Girardeau have gluten-free pizza options?
Yes, many pizzerias offer gluten-free crusts! Just ask when you order to find out what they have.

3. What is St. Louis-style pizza?
St. Louis-style pizza has a super thin crust. It also uses Provel cheese instead of mozzarella, which is really tasty!

4. Can I get pizza delivered in Cape Girardeau?
Absolutely! Most pizza places deliver right to your door. It’s so convenient for a cozy night in.

5. What are popular toppings for pizza in Cape Girardeau?
You’ll often see pepperoni, sausage, and extra cheese. Some places even have unique toppings, like BBQ chicken or veggies.

6. Are there vegan pizza options in Cape Girardeau?
Yes, some spots have vegan pizzas! You can find plant-based cheese and lots of fresh veggies.

7. Which pizza place has the best carryout?
Little Caesars is great for quick carryout. Papa Murphy’s also makes it super easy to grab a pizza to go.

8. How can I find pizza specials or discounts?
Check the websites or social media pages for deals. Many places have apps with exclusive discounts too!

9. Are there any pizza buffets in Cape Girardeau?
Yes, some restaurants do offer pizza buffets! It’s a fun way to try different kinds all at once.

10. What time do pizza places usually close in Cape Girardeau?
Most places close around 10 PM. But it’s always a good idea to check their hours before you go!